[Chemgood 한국공식대리점] RMC-9805 제품소개

[Chemgood] Product

[Chemgood] RMC-9805

 

Product Information:

• Product Name: RMC-9805
• Catalog#: C-1433
• Targets: KRAS; KRAS-G12D(ON)
• Synonym: RMC-9805; RMC 9805; RMC9805
• Chemical Formula: C63H88F3N11O7
• Molecular Weight: 1168.44
• CAS#: 2922732-54-3
• Appearance: Solid powder
• Purity: > 99% by HPLC
• Solubility: Soluble in DMSO
• Storage: Room temperature for months, or -20ºC for 3 years
• Chemical Name/IUPAC: (2S)-2-cyclopentyl-2-((S)-7-((2R,3R)-3-cyclopropyl-1-methylaziridine-2-carbonyl)-2,7-diazaspiro[4.4]nonan-2-yl)-N-((22S,63S,4S)-12-(5-(4-cyclopropylpiperazin-1-yl)-2-((S)-1-methoxyethyl)pyridin-3-yl)-10,10-dimethyl-5,7-dioxo-11-(2,2,2-trifluoroethyl)-61,62,63,64,65,66-hexahydro-11H-8-oxa-2(4,2)-morpholina-1(5,3)-indola-6(1,3)-pyridazinacycloundecaphane-4-yl)acetamide

Product Description:

RMC-9805 is a first-in-class, selective, orally-bioavailable, tri-complex covalent KRAS-G12D(ON) Inhibitor, drives profound anti-tumor activity in KRAS-G12D mutant tumor models. KRAS-G12D(ON) is the most common driver of RAS-addicted human cancers, predominantly among patients with pancreatic cancer, NSCLC, or colorectal cancer (CRC).

---